Articles

Groundbreaking Research

1) Authored landmark studies on radiofrequency transcatheter ablation for atrial fibrillation published for 3 consecutive years in Circulation, a leading journal in the field of cardiovascular medicine. These studies have been cited in 50 peer-reviewed articles. Leading study entitled “Catheter ablation of atrial fibrillation using a 3D mapping system” has itself been cited in 180 articles, including the guidelines issued by the American Heart Association/American College of
Cardiology/European Society of Cardiology for management of patients with atrial fibrillation.
2) Conducted seminal research on cardiovascular diseases, physiopathology antiarrhythmic drug therapy, asymptomatic Wolff-Parkinson White Syndrome, vagal denervation in patients undergoing AF ablation, remote navigation and ablation, progression of AF, the electrical treatment of patients with heart failure, including cardiac resynchronization therapy using multisite pacing and the novel non-excitatory electrical cardiac contractility modulation signal.
3) His ablation technique and his high-quality team work were mentioned in the article 10 Great Companies in Europe: San Raffaele, from FORTUNE, Feb 4, 2002 by Milton Moskowitz, Robert Levering, in which the San Raffaele was awarded as on the 10 best European places to work, especially in the biomedical research.
4) The article “Circumferential Radiofrequency Ablation of Pulmonary Vein Ostia: A New Anatomic Approach for Curing Atrial Fibrillation”, (see Publications cited in the Science Citation Index ref. #53) earned an Editorial “Pulmonary Vein Ablation in Atrial Fibrillation: Hype or Hope? by Hein J. J. Wellens, MD. Circulation 2000; 102: 2562-2564
5) The article entitled “Usefulness of Invasive Electrophysiologic Testing to Stratify the Risk of Arrhuthmic Events in Asymptomatic Patients With Wolff Parkinson-White Pattern. Results From a Large Prospective Long-term Follow-up Study”, (see Publications cited in the Science Citation Index ref. #43) earned an Editorial “Asymptomatic Wolff-Parkinson-White Syndrome: is it Time to Revisit Guidelines?” by Derick M. Todd et al., J Am Coll Cardiol, 2003, 41: 245-48
6) The article entitled “Mortality, morbidity, and quality of life after circumferential Pulmonary vein ablation for atrial fibrillation: Outcomes from a controlled nonrandomized long-term study”, (see Publications cited in the Science Citation Index ref. #47) earned an Editorial “Ablation of atrial fibrillation: awaiting the new paradigm” by Kenneth A. Ellenbogen and Mark A. Wood. J Am Coll Cardiol 2003 Jul 16; 42 (2),185-197.
7) The article “A Randomized Study of Prophylactic Catheter Ablation in Asymptomatic Patients with the Wolff–Parkinson–White Syndrome” (see Publications cited in the Science Citation Index ref. #48) was awarded with the Editorial High-Risk Patients with Ventricular Preexcitation — A Pendulum in Motion by Bruce B. Lerman and Craig T. Basson. THE NEW ENGLAND JOURNAL OF MEDICINE, 2003 Nov 6;349: (19) 1787-1789.
8 ) The article “First Human Chronic Experience with Cardiac Contractility Modulation by Non-Excitatory Electrical Currents for Treating Systolic Heart Failure” (see Publications cited in the Science Citation Index ref. #35) was awarded with the Editorial Comment Nonexcitatory Electrical Currents for Congestive Heart failure: Exciting or Not? by Mevan Wijetunga and S. Adam Strickberger. J Cardiovasc Electrophysiol. 2004: 428-429.
9) The article “Radiofrequency Ablation in Children with Asymptomatic Wolff-Parkinson-White Syndrome”. (see Publications cited in the Science Citation Index ref. #38) was awarded with the Editorial Catheter Ablation for Cardiac Arrhythmias by Hein J.J. Wellens. THE NEW ENGLAND JOURNAL OF MEDICINE. 2004 Sept 16; 351 (12): 1197-2005.
10) The summary of the article “Prevention of Iatrogenic Atrial Tachycardia following ablation of Atrial Fibrillation. A prospective randomized study comparing circumferential pulmonary vein ablation with a modified approach.” (see Publications cited in the Science Citation Index ref. #41) has been included in the The Journal of Evidence-based Cardiovascular Medicine, which includes summaries of only the 100 best and most useful papers published
throughout the world featuring the highest quality original research. The article Circumferential Pulmonary-Vein Ablation for Cronic Atrial Fibrillation”. (see Publications cited in the Science Citation Index ref. #19) was awarded with the Editorial Catheter Ablation of chronic atrial fibrillation- the gap between promise and practice .by Mark A. Wood and KA Ellenbogen., THE NEW ENGLAND JOURNAL OF MEDICINE, 2006;354: 967-968.
11) The article “Atrial fibrillation progression and management. A 5-year prospective follow-up study” (see Publications cited in the Science Citation Index ref. #7) earned an Editorial “Prevention of progression of atrial fibrillation: A new indication for catheter ablation?” by H Calkins. Heart Rhythm. 2008; 5 (11): 1508- 1509.
12) The article “The natural history of asymptomatic ventricular preexcitation. A long-term prospective follow-up study of 184 asymptomatic children” (see Publications cited in the Science Citation Index ref. #1) was awarded with the editorial “Asymptomatic Wolff-Parkinson-White Syndrome in Children An Unnatural History?” by Seshadri Balaji. J Am Coll Cardiol. 2009; 53: 281-283.
13) The article “Asymptomatic ventricular preexcitation: A long-term prospective follow-up study of 293 adult patients” (see Publications cited in the Science Citation Index ref. #6) earned an Editorial “WPW pattern in the asymptomatic individual. Has anything changed?” by G.J. Klein. Circ Arrhythmia Electrophysiol 2009; 2: 97-99.

Service as Reviewer and Editorial Consultant

  • Circulation
  • Lancet
  • Journal of the American College of Cardiology, Editorial Board, Editorial Consultant and from 2005 “Elite Reviewer”
  • Heart Rhythm Journal
  • European Heart Journal
  • Europace
  • Pacing and Clinical Electrophysiology
  • Journal of Cardiovascular Electrophysiology
  • Journal of Cardiovascular Medicine
  • Journal of Interventional Cardiac Electrophysiology

  • Nature Clinical Practice Cardiovascular Medicine

Scientific Interviews and Press Conferences

2000

Press release, American Heart Association: A hot tip destroys heart cells, cures atrial fibrillation.
Interview, American College of Cardiology Extended Learning (ACCEL)
Audiotapes – Circumferential Pulmonary Vein Ablation. A New Anatomic Approach for Curing Atrial Fibrillation.

2001

Press release and conference
Congress of the European Congress of Cardiology
Atrial fibrillation: is the cure at hand?
Interview, American College of Cardiology Extended Learning (ACCEL)
Audiotapes – Chronic atrial fibrillation: A Curable condition?

2003

Press release, SorinLifeWatch. Atrialfibrillation: is the cure at hand?
Interview, American College ofCardiology Extended Learning (ACCEL)
Audiotapes – Chronic atrial fibrillation: A Curable condition?

2006

Interview, American College of Cardiology 55th Annual Scientific Session
Atlanta, GA, USA, March 11-14, 2006.

Late Breaking Clinical Trial.

A Controlled Randomized Trial of Circumferential Pulmonary Vein Ablation Versus Antiarrhythmic Drug Therapy for Curing Paroxysmal Atrial Fibrillation: The Ablation for Paroxysmal Atrial Fibrillation (APAF) Trial

Professional Associations

  • Fellow, American College of Cardiology
  • Fellow, Heart Rhythm Society
  • Member, Council on Clinical Cardiology, American Heart Association
  • Honorary Member, Russian Society for Cardiac Pacing and Electrophysiology

Pubblications

( Total I.F. 745.951)

As first and corresponding author:


1. Santinelli V, Radinovic A, Manguso F, Vicedomini G, Gulletta S, G Paglino, Mazzone P, Ciconte G, Sacchi S, Sala S, Pappone C.
The natural history of asymptomatic ventricular preexcitation. A long-term prospective follow-up study of 184 asymptomatic children.
J Am Coll Cardiol. 2009; 53: 275-280.
Impact factor: 11.438
2. Pappone C and Santinelli V.
How far have we come? (In press)
Rev Esp Cardiol. 2009; 62 (10):1087-1091.
Impact factor: 2.880
3. Pappone C, Radinovic A, Manguso F, Vicedomini G, Sala S, Sacco FM, Ciconte G, Saviano M, Ferrari M, Sommariva E, Sacchi S, Ciaccio C, Santinelli V.
New-onset atrial fibrillation as first clinical manifestation of latent Brugada syndrome. Prevalence and clinical significance.
Eur. Heart J. 2009.
Impact factor: 8.917
4. Augello G, Vicedomini G, Saviano M, Crisà S, Mazzone P, Ornago O, Zuffada F, Pappone C.
Pulmonary vein isolation after circumferential pulmonary vein ablation: comparison between LASSO and 3D electroanatomical assessment of complete electrical disconnection. (In press)
Heart Rhythm 2009.
Impact factor: 4.444
5. Carpi F, Pappone C.
Stereotaxis Niobe magnetic navigation system: achievements and challenges for endocardial catheter ablation and gastrointestinal capsule endoscopy.
Expert Reviews Medical Devices 2009; 6: 5 85) 487-498.
Impact factor: 2.071
6. Carpi F. and Pappone C.
Magnetic manouvring of endoscopic capsules by means of a robotic navigation system.
IEEE Trans Biomed Eng 2009; 56 (5): 1482-1490.
Impact factor: 2.496
7. Santinelli V, Radinovic A, Manguso F, Vicedomini G, Ciconte G, Gulletta S, Paglino G, Sacchi S, Sala S, Ciaccio C, Pappone C.
Asymptomatic ventricular preexcitation: A long-term prospective follow-up study of 293 adult patients.
Circ Arrhythmia Electrophysiol 2009; 2:102-107.
8. Pappone C, Radinovic A, Manguso F, Vicedomini G, Ciconte G, Sacchi S, Mazzone P, Paglino G, Gulletta S, Sala S, Santinelli V.
Atrial fibrillation progression and management: a 5-year prospective follow-up study.
Heart Rhythm. 2008; 5 (11): 1501-1507.
Impact factor: 4.444
9. Carpi F. and Pappone C.
Magnetic robotic manoeuvring of gastrointestinal video capsules: preliminary phantom tests.
Biomed Pharmacother. 2008; 62: 546-549.
Impact factor: 2.198
10. Pappone C and Santinelli V.
Ablation of atrial fibrillation.
Eur Cardiovasc Disease. 2008; 4 (1): 96-98
11. Pappone C and Santinelli V.
Remote ablation of accessory pathways.
Eur Heart J.2008 Feb; 29 (3): 422.
Impact Factor: 8.917
12. Pappone C. and Santinelli V.
Safety and efficacy of remote magnetic ablation for atrial fibrillation
J Am Coll Cardiol. 2008;51: 1614-1615.
Impact factor: 11.438
13. Pappone C, Radinovic A and Santinelli V.
Sudden death and ventricular preexcitation: is necessary to treat the asymptomatic patients?
Curr Pharmac Design. 2008; 14 (8) 762-765.
Impact factor 4.399
14. Pappone C, Augello G, Gugliotta F, Santinelli V.
Robotic and magnetic navigation for atrial fibrillation ablation. How and why?
Expert Rev Med Devices. 2007 Nov;4(6):885-894.
Impact factor 2.071.
15. Pappone C, Santinelli V.
Non-fluoroscopic mapping as a guide for atrial ablation: current status and expectations for the future.
Eur Heart J Supplements 2007; 9: Suppl 1, 1136-1147.
Impact Factor: 2.100
16. Pappone C and Santinelli V.
Remote navigation and ablation of atrial fibrillation.
J Cardiovasc Electr 2007; 18: S18-S20. Suppl 1.
Impact Factor: 3.798
17. Pappone C and Santinelli V.
Mapping and ablation: a worldwide perspective.
J. Interv. Card. Electr. 2006 Dec; 17 (3):195-198.
Impact Factor: 1.075
18. Pappone C, Vicedomini G, Manguso F, Mazzone P, Gugliotta F, Sala S, Sora N, Paglino G, Gulletta S, Ciaccio C, Tortoriello V, Del Torchio S, Santinelli V.
Robotic Magnetic Navigation for Atrial Fibrillation Ablation.
J Am Coll Cardiol. 2006 Apr 7;47 (7): 1390-400.
Impact factor: 11.438
19. Oral H, Pappone C, Chugh A, Good E, Bogun F, Pelosi F, Bates E , Lehmann M, Vicedomini G, Augello G, Agricola E, Sala S, Santinelli V, Morady F.
Circumferential pulmonary vein ablation for chronic atrial fibrillation: a randomized, controlled study.
The New England Journal of Medicine 2006 Mar 2;354(9):934-941.
Impact Factor: 50.017
20. Oral H, Pappone C, Morady F.
Circumferential pulmonary vein ablation for chronic atrial fibrillation – Reply.
The New England Journal of Medicine 2006 Mar 2;354 (21): 2290-2291.
Impact Factor: 50.017
21. Pappone C, Santinelli V.
Substrate ablation in treatment of atrial fibrillation.
J Cardiovasc Electr 2006 17: S23-S27, Suppl: 3.
Impact factor: 3.798
22. Pappone C and Santinelli V.
How to perform encircling ablation of the left atrium.
Heart Rhythm. 2006 Sep; 3 (9) :1105-1109.
Impact Factor: 4.444
23. Pappone C, Santinelli V.
Multielectrode basket catheter: A new tool for curing atrial fibrillation.
Heart Rhythm 2006 Apr; 3(4):385-386.
Impact Factor: 4.444
24. Pappone C, Santinelli V.
Ablation of atrial fibrillation.
Curr Cardiol Rep. 2006 Sep;8(5):343-6.
25. Lang CC, Gugliotta F, Santinelli V, Mesas C, Tomita T, Vicedomini G, Augello G, Gulletta S, Mazzone P, De Cobelli F, Del Maschio A, Pappone C.
Endocardial impedance mapping during circumferential pulmonary vein ablation of atrial fibrillation differentiates between atrial and venous tissue.
Heart Rhythm. 2006 Feb; 3 (2): 171-178
Impact Factor: 4.444
26. Mesas C.E, Augello G, Edward Lang,C.C, Gugliotta F, Vicedomini, G, Sora N, De Paola A.A.V, Pappone C.
Electroanatomic remodeling of the left atrium in patients undergoing repeat pulmonary vein ablation: Mechanistic insights and implications for ablation.
J Cardiovasc Electr. 2006, Dec; 17 (12): 1279-1285.
Impact Factor: 3.798
27. Pappone C, Augello A, Sala S, Gugliotta F, Vicedomini G, Gulletta S, Paglino G, Mazzone P, Sora N, Greiss I, Santagostino A, LiVolsi L, Pappone N, Radinovic A, Manguso F and Santinelli V.
A Randomized Trial of Circumferential Pulmonary Vein Ablation versus Antiarrhythmic Drug Therapy in Paroxysmal Atrial Fibrillation. The Ablation for Paroxysmal Atrial Fibrillation (APAF) Study.
J Am Coll Cardiol. 2006 Dec 5 ;48:2340-2347.
Impact factor: 11.438
28. Lang CC, Santinelli V, Augello G, Gulleta S, Sala S, Vicedomini G, Mazzone P, Pappone C
Transcatheter Radiofrequency Ablation of atrial fibrillation in patients with mitral valve prosthetes and enlarged atria:safety, feasibility and efficacy.
J Am Coll Cardiol. 2005 Mar 15; 45 (6):868–872.
Impact Factor: 11.438
29. Triedman J, Perry J, Van Hare G, Pappone C, Santinelli V.
Risk Stratification for Prophylactic Ablation in Asymptomatic Wolff–Parkinson–White Sindrome.
The N ew England Journal of Medicine 2005; 352(1): 92-93.
Impact Factor: 50.017
30. Pappone C and Santinelli V.
Towards a unified strategy for Atrial Fibrillation?
Eur Heart J. 2005; Aug;26(16):1687-1688.
Impact factor: 9.275
31. Shanmugam G, Pappone C, Santinelli V.
Catheter ablation after mitral replacement Reply.
J Am Coll Cardiol. 2005 Aug 16;46(4):739-740.
Impact factor: 11.438
32. Pappone C and Santinelli V.
Catheter ablation should be performed in asymptomatic patients with Wolff-Parkinson-White syndrome.
Circulation. 2005 Oct 4;112(14):2207- 2215.
Impact factor: 14.595
33. Pappone C and Santinelli V.
Atrial fibrillation ablation: a realistic alternative to pharmacologic therapy.
Nat Clin Pract Cardiovasc Med. 2005 Dec;2(12):608-609.
34. Pappone C and Santinelli V.
Atrial fibrillation ablation: state of the art.
Am J Cardiol. 2005 Dec 19; 96(12 A): 59-64.
Impact factor: 3.905
35. Pappone C, Santinelli V, Manguso F, Vicedomini G, Gugliotta F, Augello G, Mazzone P, Tortoriello V, Landoni G, Zangrillo A, Lang C, Tomita T, Mesas C, Mastella E, Alfieri O.
Pulmonary vein denervation enhances long-term benefit after circumferential ablation for paroxysmal atrial fibrillation
Circulation. 2004 Jan 27; 109 (3): 327-334.
Impact factor: 14.595
36. Pappone C, Augello G, Rosanio S, Vicedomini G, Santinelli V, Romano M,Agricola E, Maggi F, Buchmayr G, Moretti G, Mika Y, Ben-Haim SA, Wolzt M, Stix G, Schmidinger H.
First human chronic experience with cardiac contractility modulation by non-excitatory electrical currents for treating systolic heart failure.
J. Cardiovasc. Electr. 2004; 15(4): 418-427.
Impact factor: 3.798
37. Pappone C, Oral H, Santinelli V, Vicedomini G, Lang CC, Manguso F, Torracca L, Benussi S, Alfieri O, Hong R, Lau W, Hirata K, Shikuma N, Hall B, Morady F.
Atrioesophageal fistula as a complication of percutaneous transcatheter ablation of atrial fibrillation.
Circulation. 2004 Jun 8:109 (22):2724-26.
Impact factor:14.595
38. Mesas CE, Pappone C, Lang CC, Gugliotta F, Tomita T, Vicedomini G, Sala S, Paglino G, Gulletta S, Ferro A, Santinelli V.
Left atrial tachycardia after circumferential pulmonary vein ablation for atrial fibrillation: Electroanatomic characterization and treatment.
J Am Coll Cardiol. 2004 Sept 1; 44 (5): 1071-1079.
Impact Factor 11.438
39. Pappone C, Manguso F, Vicedomini G, Sala S, Paglino G, Mazzone P, Lang CC, Gulletta S, Augello G,Santinelli V.
Radiofrequency Ablation in Children with Asymptomatic Wolff-Parkinson-White Syndrome.
The N ew England Journal of Medicine 2004 Sept 16;351 (12): 1197-1205.
Impact Factor:50.017
40. Pappone C and Santinelli V.
Prevention of Atrial Fibrillation: How important is transseptal atrial conduction in humans?
J Cardiovasc Electr. 2004 Oct; 15(10): 1118- 1119.
Impact factor: 3.798
41. Pappone C and Santinelli V.
The who, what, why, and how-to guide for circumferential pulmonary vein ablation.
J Cardiovasc Electrophysiol. 2004 Oct; 15 (10):1226-1230.
Impact factor: 3.798
42. Pappone C, Vicedomini G and Santinelli V.
Prevention of Iatrogenic Atrial Tachycardia following ablation of Atrial Fibrillation. A prospective randomized study comparing circumferential pulmonary vein ablation with a modified approach.
Circulation. 2004 Nov 9; 110 (19): 3036-3042.
Impact factor: 14.595
43. Pappone C, Santinelli V.
Segmental pulmonary vein isolation versus the circumferential approach: Is the tide turning? Heart Rhythm 2004; 1 (3): 326-328.
Impact Factor: 4.444
44. Pappone C, Santinelli V, Rosanio S, Vicedomini G, Nardi S, Pappone A, Tortoriello
V, Manguso F, Mazzone P, Gulletta S, Oreto G, Alfieri O.
Usefulness of invasive electrophysiologic testing to stratify the risk of arrhithmic events in asymptomatic patients with Wolff-Parkinson-White Pattern. Results from a large prospective longterm follow-up.study.
J Am Coll Cardiol. 2003; 41, 2: 239-244.
Impact factor: 11.438
45. Pappone C,
Pulmonary Vein Stenosis after Catheter Ablation for Atrial Fibrillation.
J Cardiovasc Electrophysiol 2003 Feb; 14 (2): 165-167.
Impact Factor: 3.798
46. Pappone C, Rosanio S.
Evolution of non-pharmacological curative therapy for atrial fibrillation. Where do we stand today?
Int J Cardiol. 2003 Apr; 88: 135-142.

Impact factor: 3.121

47. Pappone C, Vicedomini G, Augello G, Nardi S, Mazzone P, Rosanio S.
Combining electric therapies for advanced heart failure: The Milan experience with biventricular pacing-defibrillation backup combination for primary prevention of sudden cardiac death.
Am J Cardiol. 2003 May 8; 91(9A):74-80.
Impact factor: 3.905
48. Pappone C, Rosanio S, Augello G, Gallus G, Vicedomini G, Mazzone P, Gulletta S, Gugliotta F, Pappone A, Santinelli V, Tortoriello V, Sala S, Zangrillo A, Crescenzi G, Benussi S, Alfieri O.
Mortality, Morbidity and Quality of Life after Circumferential Pulmonary Vein Ablation for Atrial Fibrillation. Outcomes from a Controlled not Randomized Long-Term Study.
J Am Coll Cardiol. 2003 Jul 16; 42 (2):185-197.
Impact factor: 11.438
49. Pappone C, Santinelli V, Manguso F, Augello G, Santinelli O, Vicedomini G, Gulletta
G, Mazzone P, Tortoriello V, Pappone A, Dicandia C, and Rosanio S.
A Randomized Study of Prophylactic Catheter Ablation in Asymptomatic Patients with the Wolff–Parkinson–White Syndrome.
The N ew England Journal of Medicine 2003 Nov 6; 349:1803-1811.
Impact factor: 50.017
50. Pappone C, Rosanio S, Burkhoff D, Mika Y, Vicedomini G, Augello G, Shemer I, Prutchi D, Haddad W, Aviv R.
Cardiac contractility modulation by electrical currents applied during the refractory period in Patients With Heart Failure Secondary to Ischemic or Idiopathic Dilated Cardiomyopathy.
Am J Cardiol. 2002;90:1307- 1313.
Impact factor: 3.905
51. Pappone C,
Atrial fibrillation – a curable condition?
Eur Heart J. 2002 23(7):514-517.
Impact factor: 9.275.
52. Pappone C, Vicedomini G, Salvati A, Meloni C, Haddad W, Aviv R, Mika Y, Kronzon I.
Electrical modulation of cardiac contractility: Clinical aspects in congestive heart failure.
Heart Fail Rev. 2001 Jan; 6: 55-60.
Impact factor: 4.015
53. Pappone C, Oreto G, Rosanio S, Vicedomini G, Tocchi M, Gugliotta F, Salvati A, Dicandia C, Calabro MP, Mazzone P, Ficarra E, Di Gioia C, Gulletta S, Nardi S, Santinelli V, Benussi S, Alfieri O.
Atrial electroanatomic remodeling after circumferential radiofrequency pulmonary vein ablation.
Circulation. 2001; 104 (21):2539-2544, 2001.
Impact factor: 12.755
54. Pappone C, Rosanio S, Oreto G, Tocchi M, Salvati A, Dicandia C, Mazzone P, Santinelli V, Gulletta S, Vicedomini G.
Circumferential Radiofrequency Ablation of Pulmonary Vein Ostia: A New Anatomic Approach for Curing Atrial Fibrillation.
Circulation. 2000 Nov 21; 102 (21): 2619-2628.
Impact factor: 14.595
55. Pappone C, Oreto G, Lamberti F, Vicedomini G, Loricchio ML, Shpun S, Rillo M, Calabro MP, Conversano A, Ben-Haim SA, Cappato R, Chierchia S.
Catheter ablation of paroxysmal atrial fibrillation using a 3D mapping system.
Circulation. 1999 Sept 14; 100 (11):1203-1208.
Impact factor: 14.595
56. Pappone C, Stabile G, Oreto G, De Simone A, Rillo M, Mazzone P, Cappato R, Chierchia S
Inappropriate sinus tachycardia after radiofrequency ablation of para- Hisian accessory pathways.
J Cardiovasc Electrophysiol. 1997 Dec; 8 (12): 1357-1365.
Impact factor: 3.798
57. Pappone C, Stabile G, De Simone A, Senatore G, Turco P, Damiano M, Iorio D, Spampanato N, Chiariello M.
Role of Catheter-Induced Mechanical Trauma in Localization of Target Sites of Radiofrequency Ablation in Automatic Atrial Tachycardia.
J Am Coll Cardiol 1996 Apr; 27 (5);1090-1097.
Impact factor: 11.438
58. Pappone C, Lamberti F, Stabile G, De Simone A, Santomauro M, Turco P, Senatore G,
ChiarielloM.
Radiofrequency ablation in Wolff-Parkinson-White syndrome: Criteria for identification of ideal ablation sites.
New Trends in Arrhythmias 1993; 9 (3): 393
59. Pappone C, Spampinato N, Lamberti F, Santomauro M, Di Pietro M, Tortoriello V, Rillo M, Chiariello M.
Antitachycardiac pacemaker in the control of ventricular tachycardias.
New Trends in Arrhythmias 1992; 8 (1-2): 249

As co-author:

60. Padeletti L, Pappone C, Curnis A, Zanotto G, Calò L, Ricciardi G, Pieragnoli P, Dondina C, Raciti G, Michelucci A
Product-experience reporting on endocardial defibrillation leads: a 4-year national perspective.
Expert Review Medical Devices 2009; 6 (4): 383-388.
Impact factor: 2.071
61. Lunati M, Gasparini M, Santini M, Landolina M, Perego GB, Pappone C, Marzegalli M, Argiolas C, Murthy A, Valsecchi.
Follow-Up of CRT-ICD: Implications for the Use of Remote Follow-Up Systems. Data from the InSync ICD Italian Registry.
Pacing Clin Electrophysiol. 2008 Jan;31(1): 38-46.
Impact Factor: 1.590
62. Calkins H, Brugada J, Packer D, Cappato R, Chen S, Crijns H, Damiano Jr R., Davies D, Haines D, Haissaguerre M, Iesaka Y, Jackman W, Jais P, Kottkamp H, Kuck KH, Lindsay BD, Marchlinski FE, McCarthy PM, Mont JL, Morady F, Nademanee K, Natale A, Pappone C, Prystowsky E, Raviele A, Ruskin JN, Shemin RJ.
HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation: Recommendations for Personnel, Policy, Procedures and Follow-Up.
A report of the Heart Rhythm Society (HRS) Task Force on Catheter and Surgical Ablation of Atrial Fibrillation.
Developed in partnership with the European Heart Rhythm Association (EHRA) and the European Cardiac Arrhythmia Society (ECAS); in collaboration with the American College of Cardiology (ACC), American Heart Association (AHA), and the Society of Thoracic Surgeons (STS). Endorsed and Approved by the governing bodies of the American College of Cardiology, the American Heart Association, the European Cardiac Arrhythmia Society, the European Heart Rhythm Association, the Society of Thoracic Surgeons, and the Heart Rhythm
Society.
Europace. 2007 June; 9 (6):335-379.
Impact Factor: 1.706
63. Calkins H, Brugada J, Packer D, Cappato R, Chen S, H. Crijns H R, Damiano Jr R.,
Davies D, Haines D, Haissaguerre M, Iesaka Y, Jackman W, Jais P, Kottkamp H, Kuck
KH, Lindsay BD, Marchlinski FE, McCarthy PM, Mont JL, Morady F, Nademanee K,
Natale A, Pappone C, Prystowsky E, Raviele A, Ruskin JN, Shemin RJ.
HRS/EHRA/ECAS Expert Consensus Statement on Catheter and Surgical Ablation of
Atrial Fibrillation: Recommendations for Personnel, Policy, Procedures and Follow-Up.
A report of the Heart Rhythm Society (HRS) Task Force on Catheter and Surgical
Ablation of Atrial Fibrillation.
Heart Rhythm. 2007 June; 4 (6): 816-861.
Impact Factor: 4.444.
64. Natale A, Raviele A, Arentz T, Calkins H, Chen SA, Haissaguerre M, Hindricks G, Ho Y, Kuck KH, Marchlinski F, Napolitano C, Packer D, Pappone C, Prystowsky EN, Schilling R, Shah D, Themistoclakis S, Verma A.
Venice Chart international consensus document on atrial fibrillation ablation.
J Cardiovasc Electr. 2007; May;18 (5): 560- 580.
Impact factor: 3.798
65. Agricola E, Oppizzi M, Galderisi M, Pisani M, Meris A, Pappone C, Margonato A.
Role of regional mechanical dyssynchrony as a determinant of functional mitral regurgitation in patients with left ventricular systolic dysfunction.
Heart. 2006 Oct; 92 (10):1390-1395.
Impact Factor 4.964
66. Ostermayer SH, Bayard Y, Billinger K, Trepels T, Krumsdorf U, Sievert H, Reisman M, Kramer PH, Matthews RV, Block PC, Omran H, Bartorelli AL, Della Bella P, Dimario C, Pappone C, Casale PN, Gray WA, Moses JW, Poppas A, Williams DO, Meier B, Skanes A, Teirstein PS, Lesh MD, Nakai T, Sievert H.
Reply to “Does percutaneous closure of the left atrial appendage prevent stroke in atrial fibrillation?”
J Am Coll Cardiol. 2006 Apr 7;47(7):1500-1501.
Impact Factor 11.438
67. Lawo T, Borggrefe M, Butter C, Hindricks G, Schmidinge H, Mika Y, Burkhoff D,
Pappone C, Sabbah H.N.
Electrical Signals Applied During the Absolute Refractory Period An Investigational Treatment for Advanced Heart Failure in Patients With Normal QRS Duration.
J Am Coll Cardiol. 2005 Dec 20; 46 (12): 2229-2239.
Impact Factor 11.438
68. Corradi D, Callegari S, Benussi S, Maestri R, Pastori P,Nascimbene S, Bosio S, Dorigo
E, Grassan C, Rusconi R, Vettori M V, Alinovi R , Astorri E , Pappone C, Alfieri O.
Myocyte changes and their left atrial distribution in patients with chronic atrial fibrillation related to mitral valve disease.
Hum Pathol. 2005 Oct; 36, (10) 1080– 1089.
Impact factor: 7.033
69. Benussi S, Nascimbene S, Calori G, Denti P, Ziskind Z, Kassem S, La Canna G,
Pappone C, Alfieri O.
Surgical ablation of atrial fibrillation with a novel bipolar radiofrequency device.
J Thorac Cardiovasc Surg. 2005 Aug;130 (2):491-497.
Impact factor: 3.037
70. Ostermayer SH, Reisman M, Kramer PH, Matthews RV, Gray WA, Block PC, Omran H, Bartorelli AL, Della Bella P, Di Mario C, Pappone C, Casale PN, Moses JW, Poppas A, Williams DO, Meier B, Skanes A, Teirstein PS, Lesh MD, Nakai T, Bayard Y, Billinger K, Trepels T, Krumsdorf U, Sievert H.
Percutaneous Left Atrial Appendage Transcatheter Occlusion (PLAATO System) to Prevent Stroke in High-Risk Patients With Non-Rheumatic Atrial Fibrillation: Results From the International Multi-Center Feasibility Trials.
J Am Coll Cardiol. 2005 Jul 5;46(1):9-14.
Impact Factor 11.438
71. Zangrillo A, Crescenzi G, Landoni G, Benussi S, Crivellari M, Pappalardo F, Dorigo E, Pappone C, Alfieri O.
The effect of concomitant radiofrequency ablation and surgical technique (repair versus replacement) on release of cardiac biomarkers during mitral valve surgery.
Anesth Analg. 2005 Jul;101(1):24-29.
Impact Factor: 2.590
72. Zangrillo A, Landoni G, Crescenzi G, Scandroglio AM, Calabro MG, Mantovani L, Franco A, Pappone C.
A 20-joule electrical cardioversion applied directly to the heart elevates troponin I by at least 1.5 ng.mL-1.
Can J Anaesth. 2005 Mar; 52(3):336-337.
Impact factor: 2.051
73. Corradi D, Callegari S, Benussi S, Nascimbene S, Pastori P, Calvi S, Maestri R, Astorri E, Pappone C, Alfieri O
Regional left atrial interstitial remodeling in patients with chronic atrial fibrillation undergoing mitral-valve surgery.
Virchows Arch. 2004 Nov; 445 (5) :498-505.
Impact factor: 2.082
74. Bombelli F, Lagona F, Salvati A, Catalfamo L, Ferrari AG, Pappone C
Radiofrequency catheter ablation in drug refractory maternal supraventricular tachycardias in advanced pregnancy.
Obstet Gynecol. 2003 Nov;102 (5 Pt 2):1171- 1173.
Impact factor: 4.397
75. Melo JQ, Benussi S, Tortoriello W, Santinelli V, Calvi S, Nascimbene S, Pappone C, Alfieri O.
Origin of atrial fibrillation from the pulmonary veins in a mitral patient.
J Thorac Cardiovasc Surg. 2003, Sept; 126: 914-916.
Impact factor: 3.037
76. Favale S, Pappone C, Nacci F, Fino F, Resta F, and Dicandia C.
Sudden Death due to Atrial Fibrillation in Hypertrophic Cardiomyopathy: a Predictable Event in a Young Patient.
Pacing Clin Electrphysiol. 2003 Feb 26; (2 P 1): 637-639.
Impact factor: 1.590
77. Martinez-Rubio A, Cohen R, Gioffredi M, Block M, Borggrefe M, Breithardt G, Fedele F, Mäkijärvi M, Pappone C, Merino JL, Barón G.
Advances for treating in-hospital cardiac arrest. Safety and effectiveness of a new automatic external cardioverterdefibrillator.
J Am Coll Cardiol. 2003 Feb 19; 41 (4): 627–32.
Impact factor: 11.438
78. Benussi S, Nascimbene S, Agricola E, Calori G, Calvi S, Caldarola A, Oppizzi M, Casati V, Pappone C and Alfieri O
Surgical Ablation of Atrial Fibrillation Using the Epicardial Radiofrequency Approach: Mid-Term Results and Risk Analysis.
Ann Thorac Surg. 2002; 74:1050-1057.
Impact factor: 2.689
79. Priori SG, Napolitano C, Gasparini M, Pappone C, Della Bella P, Giordano U, Bloise R, Giustetto C, De Nardis R, Grillo M, Ronchetti E, Faggiano G, Nastoli J.
Natural History of Brugada Syndrome: Insights for risk stratification and management.
Circulation, 2002 March 19;105(11): 1342-1347.
Impact factor: 14.595
80. Oreto G, Luzza F, Badessa F, Calabro’ MP, Mazzone P, Careri S, Saporito F, Pappone C.
QRS complex voltage changes associated with supraventricular tachycardia.
J Cardiovasc Electrl. 2001;12:1358-1362.
Impact factor: 3.798
81. Marci M, Ziino O, D’Angelo P, Miranda G, Pappone C, Battaglia A.
Fibroma of the left ventricle in a patient with Sotos syndrome.
Echocardiography. 2001 Feb; 18 (2):171-173.
Impact factor: 444
82. Rosano GM, Leonardo F, Dicandia C, Sheiban I, Pagnotta P, Pappone C, Chierchia SL.
Acute effect of estradiol 17beta in menopausal women.
Am J Cardiol. 2000 Dec 15; 86:1385-1387.
Impact factor: 3.905
83. Priori S, Napolitano C, Gasparini M, Pappone C, Della Bella P, Brignole M, Giordano U, Giovannini T, Menozzi C, Bloise R, Crotti L, Terreni L, Schwartz P.
Clinical and genetic heterogeneity of the right bundle branch block and ST segment elevation syndrome. A prospective evaluation of 52 families.
Circulation. 2000 Nov 14; 102: 2509-2515.
Impact factor: 14.595
84. Benussi S, Pappone C, Nascimbene S, Oreto G, Caldarola A, Stefano PL, Casati V, Alfieri O.
A simple way to treat chronic atrial fibrillation during mitral valve surgery: the epicardial radiofrequency approach.
Eur J Cardio-thorac Surg. 2000. May; 17 (5):524-529.
Impact factor: 2.181
85. Fraticelli A, Saccomanno G, Pappone C, Oreto G.
Paroxysmal supraventricular tachycardia caused by 1:2 atrioventricular conduction in the presence of dual atrioventricular nodal pathways.
J Electrocardiol 1999 Oct;32 (4):347-354.
Impact factor: 1.126
86. Furlanello F, Bertoldi A, Dallago M, Galassi A, Fernando F, Biffi A, Mazzone P, Pappone C, Chierchia S.
Atrial fibrillation in elite athletes.
J Cardiovasc Electr. 1998 Aug;9 (8 Suppl):S63-68.
Impact factor: 3.798
87. Furlanello F, Bertoldi A, Dallago M, Furlanello C, Fernando F, Inama G, Pappone C, Chierchia S.
Cardiac arrest and sudden death in competitive athletes with arrhythmogenic right ventricular dysplasia.
Pacing Clin Electrophysiol. 1998 Jan;21(1 Pt 2):331-335.
Impact factor: 1.590
88. Rosano GM, Rillo M, Leonardo F, Pappone C, Chierchia SL.
Palpitations: what is the mechanism, and when should we treat them?
Int J Fertil Women Med. 1997;42(2):94- 100.
Impact factor: 0.556
89. Betocchi S, Losi M A, Piscione F, Boccalatte M, Pace L, Golino P, Perrone-Filardi C. Briguori, Franculli F, Pappone C, Salvatore M, Chiariello M.
Effects of Dual- Chamber Pacing in Hypertrophic Cardiomyopathy on Left Ventricular Outflow Tract Obstruction and on Diastolic Function.
Am J Cardiol. 1996 Mar 1; 77 (7): 498-502.
Impact factor: 3.905
90. Santomauro M, Damiano M, Pappone C, Romano M, Telese M, Lamberti F, Condorelli, M, Chiariello M.
The Anaerobic Threshold in the Evaluation of Cardiac Function in Patients with Rate Responsive Pacemakers.
Eur. J Cardiac Pacing Electrophysiol, 1994, 1: 27-33.
91. Golino A, Pappone C, Panza A, Santomauro M, Iorio D, De Amicis V, Chiariello M, Spampinato N.
Clinical Experience with the Transvenous Medtronic Pacer Cardioverter Defibrillator (PCD) System.
Tex Heart Inst J. 1993; 20: 264-270.
Impact factor: 0.873
92. Santomauro M, Fazio S, Ferraro S, Maddalena G, Papaccioli G, Pappone C, Sacca L, Chiariello M.
Follow-up of a respiratory rate modulated pacemaker.
Pacing Clin Electrophysiol. 1992 Jan;15(1):17-21.
Impact factor: 1.590
93. Santomauro M, Ferraro S, Maddalena G, Fazio S, Covino E., Pappone C, Spampinato N, Chiariello M.
Pacemaker Malfunction due to subcutaneous Emphysema.
Angiology. 1992 Oct;43 (10): 873-876.
Impact factor: 1.122
94. Santomauro M, Cuocilo A, Cementano L, Ferraro S, Pace, Pappone C, Maddalena G, Salvatore M, Chiariello M.
Diagnosis of Coronary Artery Disease with Tc 99m Methoxy Isobutil Isonitrite and Transesophageal Pacing.
Angiology. 1992 Oct; 43: (10) 818-825.
Impact factor: 1.122
95. Santomauro M, Fazio S, Ferraro S, Maddalena G, Papaccioli G, Pappone C, Betocchi S, Chiariello M.
Fourier Analysis in Patients with Different Pacing Modes.
Pacing Clin Electrophysiol. 1991 Sept;14:1351-1358.
Impact factor: 1.590